25% Off TaqMan® Probes!

Celebrating 25 Years of PCR

Dna Synthesis

Proud to having contributed to the discovery of PCR, Biosearch extends an offer on standard TaqMan probes to all new customers. Simply use the promotional code “PCR25” upon ordering and receive a 25% discount*. If you would like to begin ordering, please visit our TaqMan probes page.

Click here if you would like to see more promotional details or to learn why Biosearch is celebrating 25 years of PCR.

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High Performance Fluorescence-Quenched Probes

For your Real-time qPCR assay

CAL Fluor and Quasar Dyes

Through 20 years of industry experience, Biosearch has re-engineered and perfected probe synthesis from the ground up. We’ve formulated our fluorophores and quenchers (Black Hole Quencher®, CAL Fluor®, and Quasar®) specifically for DNA chemistry to ensure optimal signal generation of your Real-time PCR assay.

Drawing upon our vibrant dyes and dark quenchers, we carefully synthesize numerous probe and primer formats: TaqMan®, Molecular Beacons, Scorpions™, Amplifluors™, Plexors™, and BHQplus™. These sophisticated molecules can then be used in gene expression measurement, SNP detection and genotyping, environmental screening, etc.

ALL manufactured oligos are rigorously screened by LC-ESI mass spectrometry to ensure absolute confidence in their quality and performance, for applications spanning R&D to IVD.

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Not sure which probe or primer format best suits your application? Download our recently revised Probe/Primer Comparison Chart (PDF):

Probe Comparison

Biosearch People

Biosearch is committed to providing personalized service to our customers. We have gotten to know you through your ordering process. Take this opportunity to get to know the people inside Biosearch.

Joseph Knecht, Oligonucleotide Production Manager

Joe began his career in nucleic acid technology after graduating from Texas A&M University with a degree in Molecular Biology. He joined Biosearch Technologies in 2001 as an Oligonucleotide Chemist.

Trained in custom synthesis, Joe spent his first couple of years at Biosearch manufacturing and purifying custom sequences. He established synthesis, deprotection, and purification protocols for many novel proprietary fluorophores and quenchers

Currently, Joe manages day-to-day operations of Biosearch's custom oligonucleotide group. He has recently expanded manufacturing capabilities to include RNA and large scale synthesis in excess of millimolar quantities. As a pivotal leader to the production team, he continues to synthesize and purify complex custom oligonucleotides to ensure that customers can continue to rely upon Biosearch for their sophisticaed oligo conjugates.


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6/9-6/11, San Francisco, CA
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7/29-7/31, Washington, D.C.
Come visit us at Booth #101


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*Offer limited one per customer; for domestic orders only; ValuProbe and 25 nmol scale orders excluded.
Black Hole Quencher, CAL Fluor, and Quasar Dyes are registered trademarks of Biosearch Technologies, Inc.; BHQplus is a trademark of Biosearch Technologies, Inc.; TaqMan is a registered trademark of Roche Molecular Systems, Inc., Alameda, CA; Patents covering PCR are owned by Roche Molecular Systems, Inc.; Molecular Beacons for R&D purposes are manufactured for R&D applications under license issued by the Public Health Research Institute; Scorpions is a trademark of DxS, Ltd. of Manchester, UK; Amplifluor is a trademark of the Serologicals Corp.; Plexor is a trademark of Promega Corp.