Standard DNA Synthesis Reagents |
deoxyAdenosine d(A) Columns and CPGs
These supports are offered as dA(Bz) (-benzoyl) supports.
deoxyCytidine d(C) Columns and CPGs
These supports are offered as dC(Ac), (-acetyl) or dC(Bz) (-benzoyl) supports.
deoxyGuanosine d(G) Columns and CPGs
These supports are offered as dG(iBu), (-isobutryl) or dG(DMF) (-N-6 dimethylaminomethylidene) supports.
Thymidine and deoxyUridine d(U) Columns and CPGs
In addition to standard supports, we also offer 5'-DMT-T-3'-Q Linker-CPG as a support that uses a hydroquinone-0,0'-diacetic acid group (Q-linker) to attach the nucleoside to the CPG for faster cleavage (2 minutes at room temperature).
deoxyInosine & deoxyUridine Amidites
Inosine is used as a universal base, therefore it can be incorporated into any position in a synthetic oligonucleotide. 5’-DMT-dU amidite is used for the placement of deoxy uridine either internally or on the 5’ end of oligonucleotides.
deoxyInosine Columns and CPGs
Biosearch offers deoxyInosine CPG and synthesis columns. DeoxyInosine columns are packed with 1000 Å CPG, are compatible with most DNA synthesizers and are available in the following scales: 50 nmol, 200 nmol, 1 µmol.
Universal Support Columns and CPGs
Standard DNA synthesis uses supports prefunctionalized with the 3' nucleoside requiring the tedious dispensation of several different CPGs during microplate-based syntheses. This problem is circumvented by using Universal Supports (US). Universal Support gives products identical to conventional CPGs and is available in bulk or prepackaged in columns.
Mixed Base Columns and CPGs
Biosearch offers mixed base CPG and columns. Our mixed base columns are packed with 1000 Å CPG and are compatible with most DNA synthesizers. All nucleosides are linked by normal 3’ succinate linkages unless otherwise specified. DNA synthesis columns for automated synthesizers are available in the following scales: 50 nmol, 200 nmol, 1 µmol, 1.5 µmol, 3 µmol.
Aminopropyl CPGs
This CPG has been derivitized with a short linker terminating in an amine group for further derivitization. Special care is taken to exhaustively cover all available silanol groups on the native glass. This results in minimal synthesis n-1 impurities due to side silanol reactions. This linker is suitable for most synthesis applications.
These supports are offered as dA(Bz) (-benzoyl) supports.
deoxyCytidine d(C) Columns and CPGs
These supports are offered as dC(Ac), (-acetyl) or dC(Bz) (-benzoyl) supports.
deoxyGuanosine d(G) Columns and CPGs
These supports are offered as dG(iBu), (-isobutryl) or dG(DMF) (-N-6 dimethylaminomethylidene) supports.
Thymidine and deoxyUridine d(U) Columns and CPGs
In addition to standard supports, we also offer 5'-DMT-T-3'-Q Linker-CPG as a support that uses a hydroquinone-0,0'-diacetic acid group (Q-linker) to attach the nucleoside to the CPG for faster cleavage (2 minutes at room temperature).
deoxyInosine & deoxyUridine Amidites
Inosine is used as a universal base, therefore it can be incorporated into any position in a synthetic oligonucleotide. 5’-DMT-dU amidite is used for the placement of deoxy uridine either internally or on the 5’ end of oligonucleotides.
deoxyInosine Columns and CPGs
Biosearch offers deoxyInosine CPG and synthesis columns. DeoxyInosine columns are packed with 1000 Å CPG, are compatible with most DNA synthesizers and are available in the following scales: 50 nmol, 200 nmol, 1 µmol.
Universal Support Columns and CPGs
Standard DNA synthesis uses supports prefunctionalized with the 3' nucleoside requiring the tedious dispensation of several different CPGs during microplate-based syntheses. This problem is circumvented by using Universal Supports (US). Universal Support gives products identical to conventional CPGs and is available in bulk or prepackaged in columns.
Mixed Base Columns and CPGs
Biosearch offers mixed base CPG and columns. Our mixed base columns are packed with 1000 Å CPG and are compatible with most DNA synthesizers. All nucleosides are linked by normal 3’ succinate linkages unless otherwise specified. DNA synthesis columns for automated synthesizers are available in the following scales: 50 nmol, 200 nmol, 1 µmol, 1.5 µmol, 3 µmol.
Aminopropyl CPGs
This CPG has been derivitized with a short linker terminating in an amine group for further derivitization. Special care is taken to exhaustively cover all available silanol groups on the native glass. This results in minimal synthesis n-1 impurities due to side silanol reactions. This linker is suitable for most synthesis applications.
