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Support FAQs Top Questions Why does the synthesis scale ordered for my oligonucleotide not correspond with the final yield?
Support FAQs Top Questions Why does the synthesis scale ordered for my oligonucleotide not correspond with the final yield?
Why does the synthesis scale ordered for my oligonucleotide not correspond with the final yield? |
The synthesis scale and final yield are not the same because there are several steps in the synthesis of probes and primers. These steps include coupling of each base, cleavage of oligonucleotide from solid support and purification steps.
The combination of these steps cause the final yield of the oligonucleotide to be less than the synthesis scale (starting material).
