Desktop sonication device – Diagenode One
The desktop solution that provides small volume DNA and chromatin shearing for optimal sample prep.
learn moreThe desktop solution that provides small volume DNA and chromatin shearing for optimal sample prep.
learn moreAll-in-one shearing system that can simultaneously sonicate 6-16 samples.
learn moreUniformly process multiple samples in sealed tubes of 0.5 ml to 50 ml capacity.
learn moreSimple, automated, and highly reproducible device for the fragmentation of DNA from 3 kb to 75 kb.
learn moreIn recent years, advances in Next-Generation Sequencing (NGS) have revolutionized genomics and biology. This growth has fueled demands on upstream techniques for optimal sample preparation and genomic library construction. One of the most critical aspects of optimal library preparation is the quality of the DNA to be sequenced. To enable sensitive and reliable NGS results DNA must first be effectively and consistently sheared into the appropriate fragment size (depending on the sequencing platform).
To supply you with the best tools, support and quality products for your NGS projects, we've partnered with Diagenode to distribute their range of shearing instruments.* Diagenode has developed the most advanced water bath sonicators (the Bioruptor® for 150 bp – 2 kb), a unique desktop sonication device (Diagenode One® for 150 bp – 1 kb) and a unique hydrodynamic shearing instrument (the Megaruptor® for 2 kb – 75 kb). Please view the chart below for a quick overview and comparison of these instrument options
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Options |
Bioruptor Pico |
Bioruptor Plus |
Megaruptor 2 |
Diagenode One |
Recommended use | ChIP-seq and NGS sample preparation | Cell and tissue sample preparation | Ultimate solution for long read sequencing library preparation | Compact bench top device for simple NGS library preparation |
Size | 35.5 [W] x 24.5 [D] x 28 [H] cm 14 [W] x 9.6 [D] x 11 [H] in 7.9 kg (17.4 lb) |
Control unit dimensions: 35 [W] x 26 [D] x 16.5 [H] cm 13.8 [W] x 10.2 [D] x 6.5 [H] in Soundproof box dimensions: 35 [W] x 35 [D] x 26.5 [H] cm 13.8 [W] x 13.8 [D] x 10.4 [H] in 30 kg (66.1 lb) |
20 [W] x 23 [D] x 39.5 [H] cm 7.9 [W] x 9.1 [D] x 15.6 [H] in 8.2 kg (18.1 lb) |
20 [W] x 28.5 [D] x 16.5 [H] cm 7.9 [W] x 11.2 [D] x 6.5 [H] in 5 kg (11 lb) |
Key applications | Chromatin shearing 200 bp – 1 kb DNA shearing 150 bp – 1 kb RNA shearing 200 bp – 1 kb FFPE nucleic acid extraction Cell lysis and tissue disruption |
Chromatin shearing 200 bp – 1 kb DNA/RNA/Protein extraction Mass spectrometry Chemical applications |
DNA Shearing 3 kb - 75 kb (2 - 9 kb Hydropore Short and 10 - 75 kb Hydropore Long) |
DNA shearing 200 bp – 1 kb Chromatin shearing 200 bp – 1 kb |
Throughput | 16 samples (0.2 ml tube holder) 12 samples (0.1 and 0.65 ml tube holders) 6 samples (1.5 and 15 ml tube holders) |
12 (0.5 ml tube holder) 6 (1.5 ml tube holder) 6 (15 ml tube holder) 3 (50 ml tube holder) |
2 samples (process in series) | 1 sample |
Volumes | 5 - 50 µl (0.1 ml tubes) 20 - 100 µl (0.2 ml tubes) 100 µl (0.65 ml tubes) 100 - 300 µl (1.5 ml tubes) 300 µl - 2 ml (15 ml tubes) |
100 μl (0.5 ml Bioruptor tubes) 100 - 300 μl (1.5 ml Bioruptor tubes) 300 μl - 2 ml (15 ml Bioruptor tubes) 2 - 20 ml (50 ml tubes) |
50 - 400 µl (hydrotubes) Recommended: 200 µl |
20 and 50 µl |
Additional highlights | Temperature controlled Digital timer |
Temperature controlled | Temperature controlled Touchscreen with Megaruptor software |
Temperature controlled |
Need further guidance on which shearing instrument is right for you? Contact our team for a free assessment.
Automate: End repair -> Clean-up -> Adenylation -> Adapter ligation -> Stop ligation -> 2x Clean-up -> Bead size selection
* LGC’s distribution agreement includes EMEA, South America and Canada for all market sectors and the United States for the agricultural biotechnology sector.