Biosearch Technologies Expands Licensing of Roche Patents to Manufacture Kits Targeting the in-vitro Diagnostic Industry

NOVATO, CA (Tuesday, March 9, 2010) – Biosearch Technologies, Inc. (Biosearch), a leading supplier of sophisticated oligonucleotide components to the rapidly growing molecular diagnostics industry, today announced that the company has expanded its licenses from Roche Molecular Systems, Inc. (Roche). The expanded license grants Biosearch the right to manufacture and sell validated kits to the in-vitro diagnostic (IVD) marketplace as licensed products covered by multiple patents assigned to Roche. Kits sold to the IVD industry will comprise of probes, primers, enzymes, and any other essential reagents necessary to amplify and detect diagnostic targets.

Marc Beal, Director of Corporate Development at Biosearch Technologies, comments, “On September 16th, 2009, Biosearch took licenses to Roche patents covering practice of the 5’ Nuclease process, and later in the year, licensed the CDC patents describing the 2009 H1N1 and Influenza A Sub-typing signatures. With this expanded Roche license, Biosearch is poised to enter the IVD marketplace as a pivotal manufacturer of diagnostic kits.”

As the inventor and patent holder of the BHQ® (Black Hole Quencher®), CAL Fluor®, and Quasar® dye technologies, Biosearch is the sole source offering access to these proprietary dyes for research application. Furthermore, Biosearch is the only company able to synthesize them into probes for incorporation into kits for diagnostic or commercial purposes. The series of BHQ dyes have become an essential component in the highest performing, frequently demanded qPCR assays in the IVD market, including the original 2009 H1N1 influenza assays purchased by public health and other qualified laboratories worldwide.

About Biosearch Technologies, Inc.

Biosearch Technologies, Inc. is a privately held, ISO 9001:2008 certified company, located in northern California. Founded in 1993, Biosearch is a leader in the design, development and manufacture of sophisticated oligonucleotide-based tools. Products include fluorophores (CAL Fluor®, Quasar® and Pulsar® dyes) and dark quenchers (Black Hole Quencher® dyes) to be included in custom-synthesized probe formats for real-time, quantitative PCR and other genomic-based applications.

In addition to basic R&D applications, Biosearch now leverages its demonstrated expertise in fully assembled RUO kits and the cGMP manufacture of oligonucleotide components for molecular diagnostic assays. As a Class I ASR manufacturer, Biosearch’s manufacturing processes conform to all applicable GMP requirements per 21 CFR Part 820. Biosearch markets include pharmaceutical, in-vitro diagnostic, biotech, ag/bio, environmental and food testing, public health, and biodefense sectors.

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