Enabling your rapid response to the Coronavirus pandemic
Robust solutions for genetic analysis of the SARS-CoV-2 virus
In a public health emergency, getting accurate diagnostic information is of the utmost importance. You also need to get that information fast. LGC enables rapid, large-scale implementation of laboratory diagnostics for COVID-19 by expediting availability of mission-critical extraction chemistries, oligos, PCR reagents, quality control solutions, and instrumentation that deliver 2019 Novel Coronavirus detection kits at scale.
It's not you, it's your oligo. Read how to mitigate the risk of oligo contamination to preserve the integrity of your COVID-19 workflow.
Developing your own kit? What do you require to develop your SARS-CoV-2 assay?Let us know how we can help.
Industry specific workflow
Secure your supply chain needs for scalable SARS-CoV-2 detection
We have mobilised all necessary resources to support global testing requirements. From nucleic acid extraction and purification to critical assay components such as enzymes, master mix, probes and primers, we enable you to respond to COVID-19 rapidly and at scale.
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Why choose Biosearch Technologies to support your COVID-19 detection programs?
With a proven track record supporting past public health crises such as the 2009 H1N1 Swine Flu outbreak, the ability to rapidly scale up oligonucleotide production to meet increased demand for pathogen detection, and high-quality, high-performance oligonucleotide products and services, Biosearch Technologies is the right DNA primer and probe synthesis and NAC synthesis reagents partner for overcoming the challenges of emerging pathogens.
“Biosearch Beats the Deadline - Yet another partner went above and beyond: Biosearch Technologies in Novato, in Northern California, produces the Black Hole Quencher dye label used for probe technology in both the five target and H1N1 assays. It increased production at the onset of the pandemic to meet US and international demand for test reagents.”
Excerpt from page 80 of “Lessons from a virus: Public Health Laboratories Respond to the H1N1 Pandemic” Association for Public Health Laboratories
The Biosearch Blog
Get more in-depth insights about COVID-19 and how LGC, Biosearch Technologies is supporting the rapid response to the pandemic from our blog.
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Tue, May 19, 2020 @ 3:18 PM
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Behind the scenes: How our oligo synthesis team contributes to the reliability of your assays
Thu, Apr 30, 2020 @ 9:13 PM
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When you don’t need an EUA for SARS-CoV-2 testing
Fri, Apr 10, 2020 @ 10:00 PM
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Tue, Mar 31, 2020 @ 5:13 PM
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Tue, Mar 24, 2020 @ 6:58 PM
Product info access
Automation-compatible products for high-quality RNA extraction and purification from a range of clinical samples, including upper respiratory specimens.
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Bead-based nucleic acid purification chemistry that enables automated high-throughput extraction and purification of high quality RNA.
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QuickExtract™ RNA Extraction Kit
Automatable, solution-based method enabling ultra-fast extraction of RNA for expedited workflows.
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QuickExtract™ DNA Extraction Kit
Used in a fast, efficient, easily automatable one-step RNA extraction method: Sentmanat, et al. One-stepRNA extraction for RT-qPCR detection of 2019-nCoV. bioRxiv preprint
High-performance reverse transcriptase (RT) options that can fit into a range of workflows.
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EpiScript™ RNase H- Reverse Transcriptase
Reverse Transcriptase for efficient and stable cDNA synthesis at temperatures up to 55 °C.
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RapiDxFire™ qPCR 5X Master Mix GF
Robust, glycerol-free, master mix utilising RapiDxFire Hot Start Taq DNA Polymerase for sensitive, multiplex qPCR or RT-qPCR (with Episcript RNase H- Reverse Transcriptase).
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MMLV High Performance Reverse Transcriptase
Standard reverse transcriptase for temperatures up to 37 °C.
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RapiDxFire Thermostable Reverse Transcriptase
A novel lyo-compatible, thermostable reverse transcriptase, enabling high temperature cDNA synthesis from complex RNAs
Sensitive pathogen detection with our trusted master mix reagents.
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LavaLAMP RNA Master Mix and LavaLAMP RNA Component Kit
Optimised and flexible kits for and polymerase rapid isothermal amplification and detection of viral RNA, POC (lyo-compatible).
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Bst DNA Polymerase, Exonuclease Minus
Isothermal DNA polymerase for use in single-step nucleic acid amplification methods such as LAMP.
Custom synthesised and pre-designed probes and primers
A ready-to-use, out-of-the-box solution for high complexity CLIA labs running the CDC EUA protocol.
Pick and choose which COVID-19 signatures work best for your lab with individual RUO probes and primers using sequences as designated by Charité and US CDC protocols:
Custom, bulk oligos that can scale with demand
Nucleic Acid Chemistry reagents for in-house synthesis
We are the inventor and source manufacturer of BHQ™ and BBQ™ dyes, not to mention CAL Fluor™ and Quasar™ products, and support oligonucleotide synthesis with decades of combined expertise and experience from our Prime Synthesis, BioAutomation, LINK and Berry & Associates brands.
LGC SeraCare offer a complete Quality Solution for COVID-19 diagnostic assay validation
AccuPlex™ technology mimics wild-type pathogenic viruses, but is safe, non-infectious, and replication deficient. These materials serve as true, full-process quality solutions that challenge the entire diagnostic workflow, making them the preferred alternative to infectious materials.
Together, the AccuPlex SARS-CoV-2 Verification Panel and AccuPlex SARS-CoV-2 Reference Material Kit offer an ideal solution for clinical laboratories looking for a safe, effective tool to verify and monitor SARS-CoV-2 molecular assay performance. Products contain positive materials directed against the published CDC and WHO consensus sequences and the S gene. Negative materials targeting the human RNase P gene are also included.
“We just went ‘live’ with the SARS-CoV-2 assay…I’ve never brought in and validated an assay in 7 days. The LGC SeraCare reference material works perfectly. I needed something other than the assay’s positive control to create a positive assay result before I felt comfortable releasing the assay for patient testing, and your product did the trick.”
Medical Director, Clinical Chemistry Laboratory prominent Boston Academic Medical Hospital
For testing
LGC, Biosearch Technologies' oKtopure™ and IntelliQube™ instrumentation can alleviate sample preparation and testing bottlenecks with ultra-high-throughput instrumentation that was originally developed for the leaders in seed genetics. While these instruments are RUO, they are increasingly being used in CLIA labs as they offer far greater throughput for both nucleic acid extraction and qPCR-based detection than any other instrumentation on the market.
Designed for genetic target testing of millions of samples per year.
Automation and reliability enables day-in and day-out operation with minimal human intervention.
Significantly increase your ability to ramp up testing capacity and speed.
A single oKtopure/IntelliQube combination can provide ~2000 sample. extractions and tests per 8-hour period depending on assay and process setup.
For oligonucleotide synthesis
To support the demands of high-throughput oligo synthesis, we offer the MerMade™ 192E and MerMade™ 192X synthesizers. The 192E (and the robotic version 192R) is especially suited to less complex probes and primers and can synthesise 192 oligos in less than 3 hours, producing a very high quality product with minimal reagent usage.
