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Nucleic acid extraction and purification reagents

LGC Biosearch Technologies offers a broad portfolio of nucleic acid isolation technologies for diverse sample types and workflow needs, including automation-compatible solutions.
QuickExtract™️ enables fast and simple DNA and RNA extraction for PCR and RT-PCR, while sbeadex™️, sbeadex™️ Lightning, and MasterPure™️ kits provide high-quality nucleic acids for all genomics downstream applications such as NGS, GBS, and cloning.

Nucleic acid purification kits

We offer innovative superparamagnetic bead-based as well as solution-based nucleic acid purification technologies for fast and convenient isolation of high-quality DNA and RNA from a broad range of sample materials and species.

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Rapid nucleic acid extraction kits

Our QuickExtract™ kits provide a fast and easy, but rather crude DNA and RNA extraction from various sample types (including plant and FFPE samples) that is sufficient for PCR applications. The simple protocol allows cost-effective high-throughput extractions using non-toxic reagents.

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View our extraction and purification brochure
Nucleic acid purification kits Rapid nucleic acid extraction kits
sbeadex Lightning™ sbeadex™ mag™ MasterPure™ QuickExtract™
Decision aid If you want top DNA quality with the simplest, fastest mag-bead based workflow on the market If you are looking for high quality DNA with high yield across many sample types with a robust, automation ready mag bead solution If you look for a flexible and cost-effective mag bead method that works with a classical polarity based binding mechanisms based on chaotropic buffers If you look for a gentle, precipitation-based chemistry that yields high-molecular weight DNA If you do not need to purify DNA but rather look for a very fast, simple and cost-effective direct PCR approach
Technology Surface-modified superparamagnetic silica coated particles Surface-modified superparamagnetic particles Superparamagnetic silica coated particles Solution-based precipitation chemistry Buffer based technology
Mechanism of action Novel simultaneous binding and washing step1 Novel two-step binding mechanism1 Classic polarity-based binding mechanism Cell debris, proteins and DNA are precipitated and separated using highly concentrated salt solutions and isopropanol Chemically based release of nucleic acids and inactivation of PCR inhibitors
Flexibility Flexible format (single, 96-well, 384-well), scalable protocols,adaption of lysis to sample material, off-the shelf and modular Kit format available Flexible format (single, 96-well, 384-well), scalable protocols,adaption of lysis to sample material Flexible format (single, 96-well, 384-well), scalable protocols,adaption of lysis to sample material Flexible format (single, 96-well), scalable protocols, adaption of volume Flexible format (single, 96-well), scalable protocols, adaption of volume
Matrices Plant material, livestock samples, tissue and cells Plant material, tissue, cells, blood, saliva, swab, plasma, serum, urine etc. bacterial Plant material, animal tissue, whole blood, buffy coat, buccal swabs, saliva, bacteria, yeast, fungi, microorganisms Plant material, cultured cells, tissue/paraffin-embedded tissue, blood, serum, plasma, saliva, sputum, urine, yeast, bacteria Plant, hair, cell cultures, tissue, buccal cells, mouse tail snips, bacteria, FFPE
Grade of automation Automated high-throughput extraction on common liquid handling systems + MagRod (magnetic rod) instruments with increased throughput vs. traditional methods Automated high-throughput extraction on common liquid handling systems + MagRod instruments Automated high-throughput extraction on common liquid handling systems + MagRod instruments Semi-automated extraction (centrifugation required) on common liquid handling systems Semi-automated extraction (heating required) on common liquid handling systems
Benefits
  • Highest-quality DNA suited for many downstream applications
  • Fastest protocol: down to 5 minutes (sample-dependent)
  • Significant savings on plastic consumables and liquid waste
  • Only one water wash step
  • No organic solvents or chaotropic salts in wash bufferse
  • No drying of beads required for evaporation of alcohols
  • Highest-quality DNA suited for many downstream applications
  • High yields
  • No drying of beads required for evaporation of alcohols
  • Wide range of sample types
  • Highest-quality DNA suited for many downstream applications
  • High flexibility of all extraction parameters
  • High yields
  • Very cost-effective
  • High-quality DNA & RNA suited for many downstream applications
  • Suited for purification of high-molecular-weight (HMW) DNA for long-read sequencing
  • Wide range of sample types
  • High yields
  • Safe and gentle protocol without hazardous chemicals
  • Fast 3–8-minute protocol
  • PCR grade DNA and RNA
  • HTP compatible
  • Cost effective

1Our surface-coated superparamagnetic particles do not require the use of vacuum filtration or centrifugation steps; hence, they are well-suited to automation.
For research use only. Not for use in diagnostic procedures.