Hear from professionals in the industry on how they tackle the world's toughest problems…with Science!

KASP technology accelerates rice improvement in South Asia

Global rice production is increasing but there is diversity in productivity across Asia, with some regions suffering yield losses from disease, adverse weather and insufficient irrigation.There is opportunity for breeders to improve both abiotic and biotic stress response with an optimised approach for their varieties in the region.

Speaker 1: Darshna Vyas - Senior Scientist, R&D
Moderator: Beth Frey - Product Manager

For over a decade many breeders have relied on microsatellites (SSRs) for marker aided selection in rice, yet these markers are costly and time-consuming to use. Recent advances in whole genome sequencing have strengthened our knowledge of Indels and Single Nucleotide Polymorphisms (SNPs), and currently there are far more SNPs and Indels available than SSRs. We have developed KASP™ (Kompetitive Allele Specific PCR) assays for markers across rice breeding lines in South Asia and facilitated the use of these markers by public and private sector rice breeders to enhance selection for target traits.

This project has led to 33 entries that are now being evaluated in pre-release yield trials in Nepal, along with a set of KASP assays that can be readily used for efficient and accurate genotyping in rice breeding programmes.

[Panel discussion] How to establish COVID-19 diagnostics and keep up with demand

To get a grip on this COVID-19 outbreak and flatten the curve of infection, extensive diagnostic testing is crucial. With the rapid increase in testing volume and the subsequent shortages on tests and components, ensuring adequate COVID-19 diagnostics has presented a real-life challenge for laboratories.

Speaker 1: Joel A. Lefferts, PhD, HCLD, DABCC
Assistant Professor of Pathology and Laboratory Medicine, Geisel School of Medicine at Dartmouth
Assistant Director of the Clinical Genomics and Advanced Technology Lab (CGAT), Dartmouth-Hitchcock Medical Center (DHMC)

Speaker 2: Steve Bogen, MD, PhD
Medical Director of Clinical Chemistry Laboratory, Tufts Medical Center
Adjunct Professor of Pathology, Tufts University School of Medicine

Speaker 3: Eric Chow, PhD
Adjunct Assistant Professor, Biochemistry, UCSF
Director of the UCSF Center for Advanced Technology (CAT)
Head of Technology, Laboratory of Genomics Research

Speaker 4: Eric Morreale, PhD
Director, Marketing and Product Management LGC SeraCare

Speaker 5: Kathleen Campau, PhD
Associate Director, R&D LGC, Biosearch Technologies

Moderator Russell Garlick, PhD
Chief Scientific Officer LGC SeraCare

In this webinar, 3 leading experts will provide their practical experiences and challenges faced when developing, validating and going live with a SARS CoV-2 assay in routine diagnostics as well as address the challenges of ramping up test volumes to meet demand while maintaining quality standards. In addition, products specifically designed for SARS-CoV-2 testing, assay validation and QC that can support continued diagnostics at high volumes will be discussed by LGC experts.

Rapid Response to the Coronavirus Outbreak: How Collaboration Meets the Challenge

As the outbreak of 2019 Novel Coronavirus, also known as COVID-19, makes headlines on a daily basis, molecular diagnostic firms are rapidly responding by developing tests that assist in diagnosing the disease and support outbreak control.

Speaker 1: Joseph Featherstone - Head of Business Development with Co-Diagnostics
Speaker 2: Dr. Brent Satterfield - Chief Scientific Officer with Co-Diagnostics
Speaker 3: Dr. Geert Koene - Market Segment Manager MDx with LGC, Biosearch Technologies

Hear insights into the development of the CoPrimer COVID-19 test. The speakers will discuss how innovative design algorithms and a close partnership with a critical component supplier, LGC, Biosearch Technologies, enabled assay design and verification in seven days, making the COVID-19 test available for market. Brent will provide details of the CoPrimer technology and how the new algorithm enabled rapid assay design, while Joseph will share the latest developments toward clinical validation of the assay as well as discuss the CoDx Portable qPCR Lab and its impact in the field.

Development of a Novel Multiplex Assay: A Partnership Case Study

This webinar will provide a behind-the-scenes look at the collaborative development of a novel multiplex assay to speed detection of mosquito-borne illness in the clinical setting.

Speaker 1: Dr. Jana Kent - Senior Research Scientist from Co-Diagnostics (CoDx)
Speaker 2: Ryan Lusty - General Manager of the Magna Mosquito Abatement District in Utah
Speaker 3: Joseph Featherstone - CoDx

A pivotal part of the molecular diagnostics innovation chain that is often overlooked is the relation between critical component suppliers, test manufacturers, and end users. This webinar will address the development and utility of an innovative multiplex application for detection of Zika, dengue and chikungunya in mosquitos, enabling communities to reduce infection rates by vector control and prevent unnecessary infections and subsequent treatments.

Targeted genotyping by sequencing in routine breeding; a pragmatic application and process flow

Topics covered

  1. Criteria for successful application of GBS in breeding programs.
  2. Comparison of SeqSNP with existing targeted genotyping by sequencing technologies.
  3. Flexibility in marker numbers in probe library design.
  4. The balance between outsourcing to access technologies versus capital investment.

Speaker 1: Darshna Vyas - Senior Scientist, R&D
Speaker 2: Dr. Samuel Arvidsson - Team Leader Bioinformatics, NGS
Moderator: Joris Parmentier - Strategic Marketing Manager, NGS

The limitations of conventional Marker Assisted Selection (MAS) and Marker Assisted Backcrossing (MABC) breeding strategies through molecular marker technologies such as SSR’s, CAP’s, STS and HRM for the assessment of complex traits can be negated through the application of genomic selection (GS) and high-resolution genome-wide association study (GWAS). The webinar details the application of SeqSNP, a targeted genotyping by sequencing (GBS) technology for the estimation of breeding values (GBEV) for selection of optimal lines to be taken forward in breeding programs.

We will outline SeqSNP service as a comprehensive option (probe library design and production, DNA extraction, genotyping, data analysis) including an explanation of the technology and process flow.

Economic improvements of key traits in blueberry and cranberry through application of targeted genotyping by sequencing.

Darshna Vyas, one of our Senior Scientists, provides an overview of how plant breeders can benefit from the SeqSNP technology and improved plant sampling