Hear from professionals in the industry on how they tackle the world's toughest problems…with science.

Commercial readiness in light of IVDR

Third panel discussion in a series to help you develop an action plan

Speaker 1: Sue Spencer, Head of In Vitro Diagnostics & Principal Consultant, Qserve Group

Speaker 2: Erik Vollebregt, Founding partner, Axon Lawyers

Speaker 3: Dr Julien Senac, Global Director – IVD Focus Team, TÜV SÜD

This webinar covers:

There is no question that the European In Vitro Diagnostic Regulation (IVDR) is complex and will have far-reaching implications. How ready is your business for the implementation of the new regulations? Do you know what the role of your organisation is as defined by IVDR? Understanding and analysing your product portfolio will highlight what you need to discuss with suppliers and subcontractors to ensure you develop a robust supply chain to maintain continuity.

Our last webinar, ‘Getting ready for IVDR’, helped equip you with information to draw up an action plan. In this webinar, our panel of experts will discuss the commercial considerations in more detail. We’ll examine the new responsibilities of Economic Operators, whether your product is an IVD according to IVDR classification and explore the Research Use Only vs General Lab use in relation to IVDs.

Getting ready for IVDR

This panel discussion will help you develop an action plan to prepare for IVDR.

Speaker 1: Sue Spencer, Head of In Vitro Diagnostics & Principal Consultant, Qserve Group

Speaker 2: Erik Vollebregt, Founding partner, Axon Lawyers

Speaker 3: Dr Julien Senac, Global Director – IVD Focus Team, TÜV SÜD

This webinar covers:

While the pandemic has changed and continues to change operations in many molecular diagnostics manufacturers and clinical laboratories, the time is fast approaching when these manufacturers and laboratories will also need to comply with the In Vitro Diagnostic Regulation (IVDR). An early start is advised given the expected pressure on notified bodies leading up to May 2022. However, for many, IVDR raises more questions than answers. Do you know what you need to do to get ready for IVDR?

The second in a series of webinars to help you prepare for IVDR, this webinar will help you draw up an action plan by bringing you a panel discussion and Q&A by three leaders in the field who will share with you their tips on ‘Getting Ready for IVDR’.

Genotyping by sequencing for novel SNP discovery with less common genomes

This panel discussion covers the applications of targeted genotyping by sequencing, a useful approach for species where little or no genetic information is available.

Speaker 1: Dr. Tiago Hori,Director of Aquaculture Innovation, Atlantic Aqua Farms

Speaker 2: Nicholi Pitra, Lead Scientist Variety Development and Bioinformatics, Hopsteiner

Speaker 3: Jason Stannard, Vice President of Genotyping & Diagnostics, The Center for Aquaculture Technologies

Moderator: Joris Parmentier, Strategic Marketing Manager NGS, LGC, Biosearch Technologies

This webinar will cover:

The diversity of species means that not all breeding programs can rely on well-defined reference genomes. For many species, customized enzymes and expertise help uncover more variations and make more informative decisions on breeding selections.

Genotyping by sequencing (GBS) provides a means for SNP discovery for lesser interrogated species and unique populations where whole-genome sequencing would not be financially feasible due to complexities and larger genome sizes.

In this panel discussion, three experts discuss they improved their breeding programs in partnership with LGC, Biosearch Technologies.

Optimising DNA purification in plants for next generation sequencing applications

DNA purification is a key step in producing high-quality nucleic acids suitable for next generation sequencing (NGS) and a range of other downstream molecular genotyping techniques. Although NGS approaches are now commonly used in plant breeding programmes, the vast number of diverse plant species and their highly varied characteristics still make it difficult to purify DNA at the quality and scale required. LGC, Biosearch Technologies works with challenging plant sample types alongside customers as well as within our service labs to develop off-the-shelf and custom sbeadex™ purification workflows in tandem with our high-throughput extraction platform.

Speaker 1: Dr. Dietrich Köster, Global Product Manager, LGC, Biosearch Technologies

Speaker 2: Dr. Rob Brazas, Senior Product Manager, LGC, Biosearch Technologies

Speaker 3: Dr. Beth Frey, Product Marketing Manager, LGC Biosearch Technologies

This webinar will cover the:

  • key challenges with common NGS applications in plant research
  • impact of low- and high-quality DNA on NGS success
  • process we use to develop customised DNA purification protocols to match your specific plant species and NGS application requirements
  • recommended workflows for plant breeding, optimal agrigenomic strategies according to your breeding application, and key areas in your workstream that could benefit from high-throughput scale-up.

Application of Advanced genomics tools in aquaculture breeding programs

Our changing climate and growing population challenge the world’s food supply, especially in aquaculture, which is more prone to problems associated with climatic variability. Innovative scientists are turning to advanced genomic tools to enhance the production efficiency, sustainability, product quality and profitability of aquaculture. They’re partnering with LGC, Biosearch Technologies to help optimise their workflows for maximum genetic gain using a modern agrigenomic approach.

Speaker 1: Marine Claire Herlin, Global Genetics Manager, Cooke Aquaculture

Speaker 2: Dr. Jose Manuel Yanez, Director of R & D and Faculty, University of Chile

Speaker 3: Mitchell R. Lucas, PhD, Director of Genetics, American Penaeid Inc
Moderator: Jason Hein, LGC, Biosearch Technologies, Strategic Development Manager

This webinar will demonstrate how aquaculture breeders leverage genomic tools, such as targeted genotyping by sequencing and ultra-high-throughput PCR-based genotyping technology, to improve the accuracy of their genomic selection for enhanced survival in salmon, trout, tilapia and shrimp.

Celebrating advances in agrigenomics with “SuperSheroes”: women scientists using technology to seed global change

In the COVID-19 era, maintaining food security and agriculture supply chain resilience have never been more critical, as are the technology choices to address these challenges. In this webinar, the spotlight is on three “SuperSheroes,” women scientists who are seeding global change in agriculture by championing modern genomics that promote sustainability, efficiency, and optimal breeding workflows.

Speaker 1: Dr. Sukganah Apparow, Manager, Molecular Breeding Laboratory Sime Darby Plantation Technology Centre

Speaker 2: Dr. Inge Gazendam, Researcher, Plant Breeding Agricultural Research Council Vegetable and Ornamental plants

Speaker 3: Dr. Santatra Ravelomanantsoa, Crop improvement and Plant Health Scientist National Center of Applied Research for Rural Development, FOFIFA
Moderator: Dr. Joy Kang - APAC Regional Marketing Manager LGC, Biosearch Technologies

Join us as we travel to Malaysia to study sustainable oil palm production facilitated by a novel genetic prediction technology, Sub-Saharan Africa to discover fortified potato varieties supporting malnourished communities, and Madagascar to identify superior parental lines in amaranth.

Case Study: Deployment of High-Throughput SARS-CoV-2 Testing at UC Davis

Diverse components of the UC Davis campus have been mobilized to deploy HTP testing to provide a safe working environment and keep the pandemic under control. These efforts are being integrated with the Healthy Davis Together initiative, which is providing free testing for everyone in the City of Davis. The goal is to provide at least weekly testing combined with more frequent strategic testing. This requires rapid data analysis software that minimizes the time needed to accurately call, certify, and return results.

Speaker 1: Richard W. Michelmore, PhD - Director, Genome Center, UCD

Speaker 2: James Grayson - Senior Field Application Scientist, UgenTec

Speaker 3: Ross Higgins, MBA - Director, COVID Diagnostics Strategy and Market Development, LGC, Biosearch Technologies

The presentations will be followed by an interactive Q&A session with attendees.

IVDR in light of the COVID pandemic: the near future of in vitro diagnostic testing

The COVID-19 pandemic created a paradigm shift in modern healthcare, where regulations, protocols, and mindsets had to be reworked in just a matter of months to keep up with the pace of the virus. In particular, the in vitro diagnostic (IVD) market experienced a dynamic never seen before: SARS-CoV-2 tests were developed at a record-breaking pace amid global supply shortages as labs struggled to keep up with unprecedented demand.

Speaker: Erik Vollebregt - Founding Partner, Axon Lawyers

Although the pandemic is far from contained, the next challenge for the global IVD market lies around the corner. In Europe, the new Medical Device Regulation and IVD Regulation (IVDR) goes into effect on May 26, 2022, and will bring significant changes to the IVD testing space, with CE certification by a notified body becoming the rule rather than the exception and a new strict EU regime for in-house developed tests. Moreover, the Brexit transition period ended in December 2020 and the UK’s Medicines and Healthcare products Regulatory Agency (MHRA) has recently issued post-Brexit guidance on IVD in the UK. This will not only impact IVD manufacturers, but also have far-reaching consequences for supply chain and distribution, notified bodies, as well as clinical laboratories who are operating in Europe.

KASP technology accelerates rice improvement in South Asia

Global rice production is increasing but there is diversity in productivity across Asia, with some regions suffering yield losses from disease, adverse weather and insufficient irrigation.There is opportunity for breeders to improve both abiotic and biotic stress response with an optimised approach for their varieties in the region.

Speaker 1: Darshna Vyas - Senior Scientist, R&D
Moderator: Beth Frey - Product Manager

For over a decade many breeders have relied on microsatellites (SSRs) for marker aided selection in rice, yet these markers are costly and time-consuming to use. Recent advances in whole genome sequencing have strengthened our knowledge of Indels and Single Nucleotide Polymorphisms (SNPs), and currently there are far more SNPs and Indels available than SSRs. We have developed KASP™ (Kompetitive Allele Specific PCR) assays for markers across rice breeding lines in South Asia and facilitated the use of these markers by public and private sector rice breeders to enhance selection for target traits.

This project has led to 33 entries that are now being evaluated in pre-release yield trials in Nepal, along with a set of KASP assays that can be readily used for efficient and accurate genotyping in rice breeding programmes.

[Panel discussion] How to establish COVID-19 diagnostics and keep up with demand

To get a grip on this COVID-19 outbreak and flatten the curve of infection, extensive diagnostic testing is crucial. With the rapid increase in testing volume and the subsequent shortages on tests and components, ensuring adequate COVID-19 diagnostics has presented a real-life challenge for laboratories.

Speaker 1: Joel A. Lefferts, PhD, HCLD, DABCC
Assistant Professor of Pathology and Laboratory Medicine, Geisel School of Medicine at Dartmouth
Assistant Director of the Clinical Genomics and Advanced Technology Lab (CGAT), Dartmouth-Hitchcock Medical Center (DHMC)

Speaker 2: Steve Bogen, MD, PhD
Medical Director of Clinical Chemistry Laboratory, Tufts Medical Center
Adjunct Professor of Pathology, Tufts University School of Medicine

Speaker 3: Eric Chow, PhD
Adjunct Assistant Professor, Biochemistry, UCSF
Director of the UCSF Center for Advanced Technology (CAT)
Head of Technology, Laboratory of Genomics Research

Speaker 4: Eric Morreale, PhD
Director, Marketing and Product Management LGC SeraCare

Speaker 5: Kathleen Campau, PhD
Associate Director, R&D LGC, Biosearch Technologies

Moderator Russell Garlick, PhD
Chief Scientific Officer LGC SeraCare

In this webinar, 3 leading experts will provide their practical experiences and challenges faced when developing, validating and going live with a SARS CoV-2 assay in routine diagnostics as well as address the challenges of ramping up test volumes to meet demand while maintaining quality standards. In addition, products specifically designed for SARS-CoV-2 testing, assay validation and QC that can support continued diagnostics at high volumes will be discussed by LGC experts.

Rapid Response to the Coronavirus Outbreak: How Collaboration Meets the Challenge

As the outbreak of 2019 Novel Coronavirus, also known as COVID-19, makes headlines on a daily basis, molecular diagnostic firms are rapidly responding by developing tests that assist in diagnosing the disease and support outbreak control.

Speaker 1: Joseph Featherstone - Head of Business Development with Co-Diagnostics
Speaker 2: Dr. Brent Satterfield - Chief Scientific Officer with Co-Diagnostics
Speaker 3: Dr. Geert Koene - Market Segment Manager MDx with LGC, Biosearch Technologies

Hear insights into the development of the CoPrimer COVID-19 test. The speakers will discuss how innovative design algorithms and a close partnership with a critical component supplier, LGC, Biosearch Technologies, enabled assay design and verification in seven days, making the COVID-19 test available for market. Brent will provide details of the CoPrimer technology and how the new algorithm enabled rapid assay design, while Joseph will share the latest developments toward clinical validation of the assay as well as discuss the CoDx Portable qPCR Lab and its impact in the field.

Development of a Novel Multiplex Assay: A Partnership Case Study

This webinar will provide a behind-the-scenes look at the collaborative development of a novel multiplex assay to speed detection of mosquito-borne illness in the clinical setting.

Speaker 1: Dr. Jana Kent - Senior Research Scientist from Co-Diagnostics (CoDx)
Speaker 2: Ryan Lusty - General Manager of the Magna Mosquito Abatement District in Utah
Speaker 3: Joseph Featherstone - CoDx

A pivotal part of the molecular diagnostics innovation chain that is often overlooked is the relation between critical component suppliers, test manufacturers, and end users. This webinar will address the development and utility of an innovative multiplex application for detection of Zika, dengue and chikungunya in mosquitos, enabling communities to reduce infection rates by vector control and prevent unnecessary infections and subsequent treatments.

Targeted genotyping by sequencing in routine breeding; a pragmatic application and process flow

Topics covered

  1. Criteria for successful application of GBS in breeding programs.
  2. Comparison of SeqSNP with existing targeted genotyping by sequencing technologies.
  3. Flexibility in marker numbers in probe library design.
  4. The balance between outsourcing to access technologies versus capital investment.

Speaker 1: Darshna Vyas - Senior Scientist, R&D
Speaker 2: Dr. Samuel Arvidsson - Team Leader Bioinformatics, NGS
Moderator: Joris Parmentier - Strategic Marketing Manager, NGS

The limitations of conventional Marker Assisted Selection (MAS) and Marker Assisted Backcrossing (MABC) breeding strategies through molecular marker technologies such as SSR’s, CAP’s, STS and HRM for the assessment of complex traits can be negated through the application of genomic selection (GS) and high-resolution genome-wide association study (GWAS). The webinar details the application of SeqSNP, a targeted genotyping by sequencing (GBS) technology for the estimation of breeding values (GBEV) for selection of optimal lines to be taken forward in breeding programs.

We will outline SeqSNP service as a comprehensive option (probe library design and production, DNA extraction, genotyping, data analysis) including an explanation of the technology and process flow.

Economic improvements of key traits in blueberry and cranberry through application of targeted genotyping by sequencing.

Darshna Vyas, one of our Senior Scientists, provides an overview of how plant breeders can benefit from the SeqSNP technology and improved plant sampling