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The 5-Thio C6 modification is used to functionalize the 5' terminus of an oligonucleotide with a thiol group. Thiol modifications have become significant in the production of diagnostic probes. The free thiol can be used as a reactive handle to attach fluorescent dyes, maleimide compounds or for conjugation to proteins through disulfide linkages.

Properties:

  • Chemical Name:

    Thiol C6 SS

  • Formula:

    C12H25O5PS2

  • Molecular Weight:

    344.43

Product Usage:

  • The mass this product adds after conjugation and work-up (the additional mass seen by mass spectrometry) is:

    328.43

Storage and Handling: