Please join us for the LGC, Biosearch COVID-19 Podcast
The COVID-19 pandemic has forced unprecedented change throughout society, from lockdowns and mask
wearing to the rapid marshalling of the molecular diagnostics and therapeutic development communities
to counteract this deadly disease. In Countering Covid, a podcast brought to you by LGC, Biosearch Technologies,
our goal is to help assay developers, scientists, and clinicians gain behind-the-scenes insight into the
technologies around SARS-CoV-2 testing. Through conversations with the scientists that are building, implementing,
and reconfiguring technologies to address SARS-CoV-2 challenges, we highlight how, working together, we can make
the world a safer place.
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Focusing on the finer points of the SARS-CoV-2 testing workflow: false positives and false negatives
17 December, 2020 /
Understanding misleading COVID-19 test results
Like any diagnostic test, SARS-CoV-2 molecular diagnostic assays are affected by the appearance of false positives and false negative results. In this episode, we speak with qPCR assay, workflow, and measurement experts Jim Huggett, Tania Nolan, and James Grayson about the causes of false positives and false negatives and how to mitigate these misleading events. Along the way we also touch on limits-of-detection, the role of workflow software in supporting the production of reliable results, and important aspects of the qPCR assay that clinicians and assay developers should keep in mind.
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