Phosphoramidite used to incorporate a 5-hydroxy-modified deoxycytidine into an oligonucleotide for epigenetic studies.
Phosphoramidite used to incorporate a 2’-O-methoxyethyl-modified methyl-U into an oligonucleotide, useful for antisense RNA.
Modified nucleoside synthon.
Phenoxyacetyl (Pac) protected 2'-OTBDMS phosphoramidite for the incorporation of ribo-A into a synthetic oligonucleotide using UltraMILD conditions.
UltraMILD phenoxyacetyl (Pac) monomers are designed to withstand prolonged exposure to strongly alkaline conditions during heating with ammonium hydroxide solution.
Phosphoramidite replacement for dT that enhances base-pairing.
Phosphoramidite used to incorporate a N-methyl-modified deoxyadenosine into an oligonucleotide.
A state-of-the-art cyclooctyne for catalyst free strain-promoted, copper-free azide-alkyne cycloadditions.
Useful phosphoramidite for the installation of 2'-deoxy-5-propynyl cytidine for stabilization of duplex and triplex nucleic acids.
Phosphoramidite for the installation of a strained cyclooctyne (BCN) into an oligonucleotide for subsequent copper-free click elaboration.
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