Hydrocycler - thermal cycler

Hydrocycler²

Combining throughput, efficiency and robust design, the Hydrocycler² water bath thermal cycler offers an attractive alternative to traditional Peltier-based thermal cyclers for high-throughput PCR.

Water conducts heat – Using water to conduct heat to a PCR sample offers multiple advantages including the ability to process many plates or arrays in parallel for high throughput with minimal variation in temperature.

Fast cycling time – Cycling time is 40% faster since there’s no need to ramp temperatures up or down during the PCR cycle.

Precise temperature control – Plates and arrays automatically move between temperature baths, which remain consistent and precisely controlled.

Why choose the Hydrocycler²

Increased throughput

• Processes more than 145,000 samples in an eight-hour day*
• Supports 96-, 384-, and 1536-well formats
• Compatible with Nexar™, IntelliQube™, and Array Tape™

Efficient amplification

• Circulation Jet ensures temperature uniformity and eliminates edge effect
• Multi-bath system enhances cycling time and precision
• Minimal external heat generation—no need for air conditioning
• Compact footprint with tank covers to minimize evaporation
• Optimized protocols for plates and Array Tape

Intuitive user interface

• Simple and intuitive controls
• Integrated barcode tracking
• Report generation and log file review

Chemistry

• Supports all common end-point PCR chemistries and emulsion PCR (ePCR)
• Uniform temperature across plates and arrays for consistent results

*Throughput depends on cycling conditions and chemistry. Estimate based on 1536-plates and a standard KASP 36-cycle run totaling 1 hour 10 minutes.

Resources

• Hydrocycler² data sheet
• Hydrocycler² – How does it work
• Hydrocycler² user’s manual

Hydrocycler²

Hydrocycler² well plate basket

Hydrocycler² array tape basket