A phosphoramidite that is an isosteric analogue of dG.
Isosteric with adenine but offers a different pi-electron distribution and thus an altered dipole moment.
Useful phosphoramidite for modification of base pairing and metal chelating characterisitcs of purine nucleosides through elimination of the N7 nitrogen.
A stable phosphoramidite analogue of N3-methyladenine (3-Me-A).
Phosphoramidite for the installation of 7-Deaza-G residues in G-rich regions of oligos to disrupt unwanted hydrogen bonding.
Phosphoramidite for internal or 5'-incorporation of a deaza-modified dG nucleobase into an oligonucleotide.
Useful for incorporating 7-Deaza-modified guanosine into oligonucleotides to disrupt unwanted hydrogen bonding.
Used to oxidise the unstable trivalent phosphite triester linkage to the stable pentavalent phosphotriester during the oligo synthesis cycle.
UltraMILD phenoxyacetyl (Pac) monomers are designed to withstand prolonged exposure to strongly alkaline conditions during heating with ammonium hydroxide solution.
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